CIQTEK QDAFM - Diamond III is a magnetic imaging instrument based on both nitrogen-vacancy (NV) center in diamond and AFM scanning imaging technology. By quantum control and readout of the spin state in the diamond probe, the magnetic property of samples is acquired quantitatively and non-invasively. With nanoscale spatial resolution and ultra-high detection sensitivity, QDAFM is an innovative technology to develop and study magnetic textures, high-density magnetic storage, and spintronics.
There are two versions: the ambient version and the cryogenic version.
Single cell magnetic imaging
The in situ measurement of biomolecules inside a single cell is an important goal in life science. Among various imaging techniques, the magnetic resonance imaging (MRI) technique can quickly and non-destructively acquire spin distribution images in vivo. As MRI has almost no damage to organisms, it plays an important role in pathological research, diagnosis, and treatment of diseases. However, the spatial resolution limit of traditional MRI is above micrometers, thus it is impossible to perform molecular-scale MRI in a cell. The researchers break the limit with QDAFM, which enables a 10 nm spatial resolution magnetic imaging of ferritins in a single cell.
References：
Wang, P. et al. Nanoscale magnetic imaging of ferritins in a single cell. Science advances 5, 8038 (2019).
